The glomerular filtration barrier comprises three interdependent layers: a fenestrated endothelium coated by a glycocalyx, a specialised glomerular basement membrane and podocyte foot processes linked ...

Among patients without albuminuria, shrunken pore syndrome was associated with higher risks for HF (hazard ratio [HR], 3.07; 95% CI, 1.47-6.69), peripheral artery disease (HR, 3.64; 95% CI, 1.75-7.57) ...

Scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense promise for ...

THE kidneys are among the most important organs in the human body, yet many people rarely think about them until a problem develops. These two bean-shaped organs, located on either side of the spine ...

A team has devised a more accurate way of measuring an indicator of kidney function known as glomerular filtration rate (GFR) by taking aging into account. Annual health checkups regularly include ...

In a 60-year-old patient with clinical stage III adenocarcinoma of the lung, treatment with 160 mg of selpercatinib twice daily, in 28-day cycles, led to a rapid decrease in the estimated glomerular ...

The milestone marks a significant step forward for a technology designed to address one of healthcare's most persistent challenges. Millions of patients worldwide rely on treatments that primarily ...

In a study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the ...