Our understanding of how cells interact with each other has been driven for decades by the central concept of ...

As an embryo develops from a small cluster of stem cells, those once "blank slate" cells begin to take on more specialized ...

Natural killer cells have long been viewed as the immune system’s blunt but dependable first responders, capable of destroying tumor cells without the elaborate priming that T cells require. In r ...

Researchers at the Stanford Cardiovascular Institute have characterized an unexpected signaling pathway that helps drive ...

Most cell signals are chemical in nature. For example, prokaryotic organisms have sensors that detect nutrients and help them ...

Calcitriol, the hormonally active form of vitamin D, has long been suspected of harboring anticancer properties, but the ...

The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature. "Biochemists have been studying ion channels for decades and debating about how they work for almost ...

Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be precisely amplified to mount an effective defense against invasive threats. New ...

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns. Scientists at St. Jude Children's ...